王宗文，福建农林大学蜂学与生物医药学院、理学博士、副教授（硕士生导师）、
福建省高层次人才（C类）、电子邮箱： zwwang@fafu.edu.cn。
工作教育经历：
2023年8月-至今：福建农林大学，植物保护学院制药工程系，副教授
2017年11月-2018年11月：福建省植物保护学会，理事
2014年4月-2015年7月：美国迈阿密国际大学，高分子化学系，访问学者
2008年9月-2013年7月：福州大学化学化工学院分析化学专业，获理学博士学位
2004年9月-2008年7月：福州大学化学化工学院化学系，获理学学士学位
承担课程：现代仪器分析
研究方向：生物传感器、生物标志物检测
科研项目：
1、国家自然科学基金，21505020，构建基于核酸酶辅助信号放大策略的可卡因可视化传感器，2016/01-2018/12，21万元，结题，主持
2、福建农林大学“校杰青项目”，201810，基于核酸适配体的二氯喹啉酸快速检测方法的研究，2019/01-2021/12，30万元，结题，主持
3、福建省自然科学基金，2021J01063，基于磷酰二胺吗啉代寡核苷酸和适配体比色法快速检测除草剂二氯喹啉酸的新方法研究，2021/08-2024/07，10万元，在研，主持
4、近海流域环境测控治理福建省高校重点实验室开放课题，S1-KF2105，构建快速检测筛查近岸水环境和水生物中磺胺类抗生素的超多色比色试纸，2021/11-2023/11，2万元，结题，主持
1.Zongwen Wang*, Xiating Li, Feng Zhang, Yu Gao, Jintian Cheng, and FengFu Fu, Regulating the Growth Rate of Gold Nanobipyramids via a HCl-NADH-Ascorbic Acid System toward a Dual-Channel Multicolor Colorimetric Immunoassay for Simultaneously Screening and Detecting Multiple Sulfonamides, An-alytical Chemistry, 2023, 95, 27, 10438–10447. (化学1区, IF=7.418)
2.Zongwen Wang, Qian Chen, Yingying Zhong, Xinhui Yu, Yongning Wu, FengFu Fu*, A Multicolor Immunosensor for Sensitive Visual Detection of Breast Cancer Biomarker Based on Sensitive NADH-Ascorbic-Acid-Mediated Growth of Gold Nanobipyramids. An-alytical Chemistry, 2020, 92, 1534-1540. (化学1区, IF=6.350)
3.Zongwen Wang, Haixiang Yu, Juan Canoura, Yingzhu Liu, Obtin Alkhamis1, Fengfu Fu, Yi Xiao*, Introducing structure-switching functionality into small-molecule-binding aptamers via nuclease-directed truncation. Nucleic Acids Research, 2018, 64, e81.(生物1区, IF=11.147)
4.Juan Canoura#, Zongwen Wang#, Haixiang Yu, Obtin Alkhamis, Fengfu Fu and Yi Xiao. No Structure-Switching Required: A Generalizable Exonuclease-Mediated Aptamer-Based Assay for Small-Molecule Detection. Journal of the American Chemical Society, 2018, 140, 9961-9971.(化学1区, IF=14.695)
5.ZongWen Wang, Jing Zhang, Ying Guo, XiaoYan Wu, WeiJuan Yang, LiangJun Xu, JingHua Chen and FengFu Fu*. A novel electrically magnetic-controllable electrochemical biosensor for the ultra sensitive and specific detection of attomolar level oral cancer-related microRNA. Biosensors and Bioelectronics, 2013, 45, 108-113. (化学1区, IF = 5.437)
6.ZongWen Wang, YingWei Fan, JinFa Chen, Ying Guo, WeiHua Wu, Ye He, LiangJun Xu and FengFu Fu *. A microfluidic chip-based fluorescent biosensor for the sensitive and specific detection of label-free single-base mismatch via magnetic beads-based “sandwich” hybridization strategy. Electrophoresis, 2013, 34, 2177-2184. (化学3区, IF=3.261)
7.ZongWen Wang, JingHua Chen, YingWei Fan, WenJian Wang, FengFu Fu*. “A novel micro-fluidic biosensor for the rapid and sequence-specific detection of DNA with electrophoretic driving mode and laser-induced fluorescence detector”. Microfluid Nanofluid, 2012, 100, 338-343. (工程3区, IF=3.218)
8.ZongWen Wang, WenJian Wang, Wei Wang, LiangJun Xu, GuoNan Chen and FengFu Fu*, “Separation and determination of β-Casomorphins by using glass microfluidic chip Electrophoresis together with laser-induced fluorescence detection”. Journal of Separation Science, 2011, 34, 196-201.
9.ZongWen Wang, WenJian Wang, GuoNan Chen, Wei Wang and FengFu Fu*. Liquid chromatography on a monolithic column microfluidic chip coupled with “Three-T” sample injection mode and amperometric detection”. Journal of Separation Science, 2010, 33, 2568-2574.
10.Feng Zhang, Yu Gao, Enxi Ren, Ling Fang, Weijuan Yang, Liaoyuan Zhang, Zongwen Wang*. Paper-based multicolor sensor for on-site quantitative detection of organophosphate pesticides based on acetylcholinesterase-mediated paper-based Au3+-etching of gold nanobipyramids and CIELab color space. Talanta 2025, 281, 126925. (化学1区Top, IF=5.6)
11.Feng Zhang, Zemiao Wang,Ling Fang, Weijuan Yang, Zongwen Wang*, FengFu Fu*. Regulating Gold Nanobipyramid Morphology via Au+-Disproportionation System on Paper Toward a Paper-Based Multicolor Sensor for Sensitive Visual Detection of Acetylcholinesterase Activity. ACS Applied Nano Materials 2024, 7(17), 20933–20941. (材料科学2区, IF=5.3).
12.Feng Zhang, Enxi Ren, Zemiao Wang, Ling Fang, Weijuan Yang, Liaoyuan Zhang*, Zongwen Wang*. Portable and sensitive paper-based multicolor sensor for on-site detection of organophosphate pesticides using a high-efficiency Au+-induced gold nanobipyramids aspect ratio regulation strategy. Microchemical Journal, 2024, 207, 111912 (化学2区Top, IF=4.9).
13.Zemiao Wang, Feng Zhang, Ling Fang, Fengping Chen, Weijuan Yang*, Zongwen Wang*, Development of folding-based and signal-amplified fluorescence aptasensors using G-quadruplex quinclorac aptamer variants engineered via exonuclease digestion and circular dichroism spectroscopy, Sensors and Actuators: B. Chemical, 2024, 415, 135996. (化学1区Top, IF=8.4)
14.Qian Chen, Yuquan Pan, Chaochen Sun, Zongwen Wang*, Yongning Wu, FengFu Fu*, A multicolor immunosensor for the visual detection of six sulfonamides based on manganese dioxide nanosheet-mediated etching of gold nanobipyramids, Talanta, 2023, 258, 124449. (化学1区, IF=6.028)
15.Meiling Ping, Wenchao Lv, Chen Yang, Qian Chen, Zongwen Wang*, Fengfu Fu*, A Paper-Based Multicolor Colorimetric Aptasensor for the Visual Determination of Multiple Sulfonamides Based on Aptamer-Functionalized Magnetic Beads and NADH-Ascorbic Acid-Mediated Gold Nanobipyramids. Chemosensors, 2023, 11, 386.(化学3区, IF=4.161)
16.Lan Yang, Xingyan Ye, Xiating Li, Zhihong Huang, Fengping Chen, Weijuan Yang, Zongwen Wang*. Colorimetric aptasensor for sensitive detection of quinclorac based on exonuclease-assisted cyclic release of phosphorodiamidate morpholino oligomer mimic enzyme strategy. An-alytica Chimica Acta, 2022, 1207: 339815. (化学1区, IF=6.911)
17.Xingyan Ye, Feng Zhang, Lan Yang, Weijuan Yang, Liaoyuan Zhang, Zongwen Wang*. Paper-based multicolor sensor for on-site quantitative detection of 2,4-dichlorophenoxyacetic acid based on alkaline phosphatase-mediated gold nanobipyramids growth and colorimeter-assisted method for quantifying color. Talanta, 2022, 245: 123489. (化学1区, IF=6.057)
18.Zongwen Wang*, Lan Yang, Xingyan Ye, Chaolong Huang, Weijuan Yang, Liaoyuan Zhang, Zujian Wu, FengFu Fu*, Multicolor visual screening of total dithiocarbamate pesticides in foods based on sulfydryl-mediated growth of gold nanobipyramids. An-alytica Chimica Acta, 2020, 1139, 59-67. (化学1区, IF=5.977)
19.Xinhui Yu, Yaohui Lin, Xusheng Wang, Liangjun Xu, Zongwen Wang*, FengFu Fu*, Exonuclease-assisted multicolor aptasensor for visual detection of ochratoxin A based on G-quadruplex-hemin DNAzyme-mediated etching of gold nanorod. Microchimica Acta, 2018, 185, 259. (化学2区, IF=5.705)
20.Jinfa Chen, Fengfu Fu, Siying Wu, Jing Wang, Zongwen Wang*. Simultaneous detection of zinc dimethyldithiocarbamate and zinc ethylenebisdithiocarbamate in cabbage leaves by capillary electrophoresis with inductively coupled plasma mass spectrometry, Journal of Separation Science, 2017, 40, 3898-3904.
21.Xiong Zhang, Qiao Liu, Zongwen Wang, Hui Xu, Fengping An, Qun Huang, Hong-Bo Song*, Yiwei Wang*, D-penicillamine modified copper nanoparticles for fluorometric determination of histamine based on aggregation-induced emission. Microchimica Acta, 2020, 187, 329.
22.Ye He, Shilong Chen, Lin Huang, Zongwen Wang, Yongning Wu, and FengFu Fu*. Combination of Magnetic-Beads-Based Multiple Metal Nanoparticles Labeling with Hybridization Chain Reaction Amplification for Simultaneous Detection of Multiple Cancer Cells with Inductively Coupled Plasma Mass Spectrometry. An-alytical chemistry, 2018, 91, 1171-1177.
23.Po Wang*, Chuanyue Han, Fuyi Zhou, Jusheng Lu* Xiguang Han and Zongwen Wang. Electrochemical determination of tert-butylhydroquinone and butylated hydroxyanisole at choline functionalized film supported graphene interface. Sensors and Actuators B: Chemical, 2016, 224, 885-891.
24.Po Wang, Fuyi Zhou, Zongwen Wang, Chao Lai and Xiguang Han*. Substrate-induced assembly of PtAu alloy nanostructures at choline functionalized monolayer interface for nitrite sensing. Journal of Electroan-alytical Chemistry, 2015, 750, 36-42.
25.Ming Wei Yang, ZongWen Wang, Ling Fang, Jin Ping Zheng, Liang Jun Xu, Feng Fu Fu*. “Simultaneous and ultra-sensitive quantification of multiple peptides by using europium chelate labeling and capillary Electrophoresis-inductively coupled plasma mass spectrometry”. Journal of An-alytical Atomic Spectrometry, 2012, 27, 946-951.
26.Wei Wang, Zijian Wang, Xiuli Lin, ZongWen Wang and FengFu Fu*. Simultaneous an-alysis of seven oligopeptides in microbial fuel cell by micro-fluidic chip with reflux injection mode. Talanta, 2012, 100, 338-343
专利：
(1) 杨玮娟；罗冬冬；肖于凡；王宗文；一种特异识别二氯喹啉酸的核酸适配体及其应用，2023-05-23,中国，CN202110478099.6
(2) 王宗文；张峰；杨玮娟；一种检测乙酰胆碱酯酶活性或有机磷农药的纸基多色比色法，2023-11-24，中国，2023115862170