一、基本信息
姓 名：陈大福
性 别：男
政治面貌：中共党员
职 称：教授，博士生导师
职 务：副院长
研究方向：蜜蜂及其病原分子生物学、组学、蜜蜂疾病防控
电子邮箱：dfchen826@fafu.edu.cn
二、受教育经历
1992.09-1996.07 福建农业大学蜂学专业，学士
1996.09-1999.07 福建农业大学农业昆虫与害虫防治专业，硕士
2001.09-2004.06 浙江大学特种经济动物饲养专业，博士
三、研究工作经历
2012.02-2012.07 福建师范大学生命科学学院 访问学者
2013.12-2014.12 以色列农业部农业研究组织（ARO）昆虫系 博士后
四、科研项目
1.2020.1-2025.12，国家农业部、财政部，现代农业（蜂）产业技术体系蜜蜂细菌病与真菌病防控岗位科学家（CARS-44-KXJ7），300万元，主持，在研。
2.2022.1-2025.12，国家自然科学面上项目，circRNA-miRNA-mRNA轴介导中华蜜蜂工蜂响应东方蜜蜂微孢子虫侵染的免疫应答机制（32172792），58万，主持，在研。
3.2024.1-2027.12，国家自然科学面上项目，lncRNA/circRNA靶向miR-13b调控意大利蜜蜂幼虫应答蜜蜂球囊菌侵染的作用机制（32372943），50万，参与，在研。
4.主持国家自然科学基金青年科学基金项目、福建省自然科学基金项目、国家科技支撑项目子课题及横向课题等多个项目，已结题；参与国家自然科学基金青年科学基金项目、福建省自然科学基金项目等多项。
五、承担课程
承担本科生专业核心课程《蜜蜂保护学》、研究生《蜜蜂保护学》和《蜂学研究进展》部分课程。
六、科研成果
发表学术论文90余篇，出版教材和专著11部，获授权专利10余项。获科技成果1项（合作）；河南省科技进步奖二等奖1项（合作）；河南省教育厅科技成果奖二等奖1项（合作）。
七、代表性论文与著作
1. Zhang, K.; Fu, Z.; Fan, X.; Wang, Z.; Wang, S.; Guo, S.; Gao, X.; Zhao, H.; Jing, X.; Zou, P.; Li, Q.; Chen, M.; Chen, Da.; Guo, R. Effect of Ascosphaera apis Infestation on the Activities of Four Antioxidant Enzymes in Asian Honey Bee Larval Guts. Antioxidants, 2023, 12, 206. https://doi.org/10.3390/ antiox12010206 （共同通讯作者）
2. Zixin Wang, Siyi Wang, Xiaoxue Fan, Kaiyao Zhang, Jiaxin Zhang, Haodong Zhao, Xuze Gao, Yiqiong Zhang, Sijia Guo, Dingding Zhou, Qiming Li, Zhihao Na, Dafu Chen, Rui Guo. Systematic Characterization and Regulatory Role of lncRNAs in Asian Honey Bees Responding to Microsporidian Infestation. International Journal Molecular Sciences, 2023, 24, 5886. https:// doi.org/10.3390/ijms24065886 （共同通讯作者）
3. Wu, Y.; Guo, Y.; Fan, X.; Zhao, H.; Zhang, Y.; Guo, S.; Jing, X.; Liu, Z.; Feng, P.; Liu, X.; , Zou, P.; Li, Q.; Na, Z.; Zhang, K.; Chen, D.; Guo, R.. ame-miR-34 Modulates the Larval Body Weight and Immune Response of Apis mellifera Workers to Ascosphara apis Invasion. International Journal Molecular Sciences, 24, 1214. https://doi.org/ 10.3390/ijms24021214 （共同通讯作者）
4. Yuanchan Fan, Jie Wang, Kejun Yu, Wende Zhang, Zongbing Cai, Minghui Sun, Ying Hu, Xiao Zhao, Cuiling Xiong, Qingsheng Niu, Dafu Chen, Rui Guo. Comparative Transcriptome Investigation of Nosema ceranae Infecting Eastern Honey Bee Workers. Insects, 2022, 13, 241. https://doi.org/10.3390/insects13030241 （共同通讯作者）
5．Yan-Zhen Zheng, Yu Zhou, Geng Deng, Rui Guo, Da-Fu Chen. Structures and non-covalent interaction behaviours of binary systems containing the ionic liquid 1-(2′-hydroxylethyl)-3-methylimidazolium bis(trifluoromethylsulfonyl)imide and chloroform. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 244: 118843. （通讯作者）
6. Dafu Chen, Huazhi Chen, Yu Du, Zhiwei Zhu, Jie Wang, Sihai Geng, Cuiling Xiong, Yanzhen Zheng, Chunsheng Hou, Qingyun Diao, Rui Guo. Systematic identification of circular RNAs and corresponding regulatory networks unveil their potential roles in the midguts of eastern honeybee workers. Applied Microbiology and Biotechnology, 2020, 104: 257–276. （第一作者）
7. Dafu Chen, Yu Du, Xiaoxue Fan, Zhiwei Zhu, Haibin Jiang, Jie Wang, Yuanchan Fan, Huazhi Chen, Dingding Zhou, Cuiling Xiong, Yanzhen Zheng, Xijian Xu, Qun Luo, Rui Guo. Reconstruction and functional annotation of Ascosphaera apis full-length transcriptome utilizing PacBio long reads combined with Illumina short reads. Journal of Invertebrate Pathology, 2020, 176: 107475. （第一作者）
8. Yan-Zhen Zheng, Geng Deng, Rui Guo, Zhong-Min Fu, Da-Fu Chen. Effects of different ester chains on the antioxidant activity of caffeic acid. Bioorganic Chemistry, 2020, 105: 104341. https://doi.org/10.1016/j.bioorg.2020.104341（通讯作者）
9. Yan-Zhen Zheng, Yu Zhou, Rui Guo, Zhong-Min Fu, Da-Fu Chen. Structure-antioxidant activity relationship of ferulic acid derivatives: Effect of ester groups at the end of the carbon side chain. LWT - Food Science and Technology, 2020, 120: 108932. doi: https://doi.org/10.1016/j.lwt.2019.108932. （通讯作者）
10. Dafu Chen, Huazhi Chen, Yu Du, Dingding Zhou, Sihai Geng, Haipeng Wang, Jieqi Wan, Cuiling Xiong, Yanzhen Zheng, Rui Guo. Genome-Wide Identification of Long Non-Coding RNAs and Their Regulatory Networks Involved in Apis mellifera ligustica Response to Nosema ceranae Infection. Insects, 2019, 10, 245; doi:10.3390/insects10080245 （第一作者）
11. Dafu Chen, Yu Du, Huazhi Chen , Yuanchan Fan, Xiaoxue Fan, Zhiwei Zhu, Jie Wang, Cuiling Xiong, Yanzhen Zhen, Chunsheng Hou, Qingyun Diao, Rui Guo. Comparative Identification of MicroRNAs in Apis cerana cerana Workers’ Midguts in Response to Nosema ceranae Invasion. Insects, 2019, 10, 258; doi:10.3390/insects10090258 （第一作者）
12. Yan-Zhen Zheng, Geng Deng, Rui Guo, Da-Fu Chen, Zhong-Min Fu. DFT Studies on the Antioxidant Activity of Naringenin and Its Derivatives: Effects of the Substituents at C3. International Journal of Molecular Sciences, 2019, 20: 1450; doi:10.3390/ijms20061450 （通讯作者）
13. Yan-Zhen Zheng , Geng Deng, Rui Guo, Zhong-Min Fu, Da-Fu Chen. The influence of the H5…O=C4 intramolecular hydrogen-bond (IHB) on the antioxidative activity of flavonoid. Phytochemistry, 2019,160: 19-24. （通讯作者）
14. Yan-Zhen Zheng, Yu Zhou, Geng Deng, Rui Guo, Da-Fu Chen. Insight into the structure and interaction properties of 1-propylnitrile-3-methylimidazolium bis(trifluoromethylsulfonyl)imide and chloroform mixtures. Journal of Molecular Liquids, 2019, 283: 748-755. （通讯作者）
15. Yan-Zhen Zheng, Geng Deng, Rui Guo, Da-Fu Chen, Zhong-Min Fu. Substituent Effects on the Radical Scavenging Activity of Isoflavonoid. International Journal of Molecular Sciences, 2019, 20, 397; doi:10.3390/ijms20020397 （通讯作者）
16. Y-Z. Zheng, Z-R. Shen, Y. Zhou, R. Guo, D-F. Chen. A combination of FTIR and DFT methods to study the structure and interaction properties of TSILs and DMSO mixtures. J. Chem. Thermodynamics, 131 (2019): 441-448. doi: https://doi.org/10.1016/j.jct.2018.11.023（通讯作者）
17. Yan-Zhen Zheng, Geng Deng, Da-Fu Chen, Rui Guo, Rong-Cai Lai. The influence of C2=C3 double bond on the antiradical activity of flavonoid: Different mechanisms a/nalysis. Phytochemistry, 157 (2019): 1-7. doi: https://doi.org/10.1016/j.phytochem.2018.10.015（通讯作者）
18. Dafu Chen, Rui Guo, Cuiling Xiong, et al. Morphological and molecular identification of chalkbrood disease pathogen Ascosphaera apis in Apis cerana cerana. Journal of Apicultural Research, 2018, doi: https://doi.org/10.1080/00218839.2018.1475943（第一作者）
19. Rui Guo, Dafu Chen, Cuiling Xiong, et al. Identification of long non-coding RNAs in the chalkbrood disease pathogen Ascospheara apis. Journal of Invertebrate Pathology, 2018, doi: https://doi.org/10.1016/j.jip.2018.06.001 （通讯作者）
20. Yan-Zhen Zheng, Da-Fu Chen, Yu Zhou, et al. Hydrogen-bonding interactions between 1-butyl-2,3-dimethylimidazolium tetrafluoroborate and dimethyl sulphoxide. Journal of Molecular Structure, 2018, 1164: 70-76. （通讯作者）
21. Y-Z. Zheng, Z-R. Shen, Y. Zhou, R. Guo, D-F. Chen. A combination of FTIR and DFT methods to study the structure and interaction properties of TSILs and DMSO mixtures. J. Chem. Thermodynamics (2018), doi: https://doi.org/10.1016/j.jct.2018.11.023（通讯作者）
22. Rui Guo, Dafu Chen, Cuiling Xiong, et al. First identification of long non-coding RNAs in fungal parasite Nosema ceranae. Apidologie, 2018, 49: 660-670. （通讯作者）
23. Rui Guo, Dafu Chen, Huazhi Chen, et al. Systematic investigation of circular RNAs in Ascosphaera apis, a fungal pathogen of honeybee larvae. Gene, 2018, 678: 17-22. （通讯作者）
24. Rui Guo, Dafu Chen, Huazhi Chen, et al. Genome-Wide Identification of Circular RNAs in Fungal Parasite Nosema ceranae. Current Microbiology, https://doi.org/10.1007/s00284-018-1576-z（通讯作者）
25. Yan-Zhen Zheng, Da-Fu Chen, Geng Deng, et al. The antioxidative activity of piceatannol and its different derivatives: Antioxidative mechanism a/nalysis. Phytochemistry, 156 (2018) 184–192. （通讯作者）
26. Yan-Zhen Zheng, Geng Deng, Da-Fu Chen, et al. Theoretical studies on the antioxidant activity of pinobanksin and its ester derivatives: Effects of the chain length and solvent. Food Chemistry, 2018, 240: 323-329. （通讯作者）
27. Dafu Chen, Rui Guo, Xijian Xu, et al. Uncovering the immune responses of Apis mellifera ligustica larval gut to Ascosphaera apis infection utilizing transcriptome sequencing. Gene, 2017, 621: 40-50. （第一作者）
28. Yan-Zhen Zheng, Jing Xu, Qin Liang, Da-Fu Chen, et al. A density functional theory study on the hydrogen bonding interactions between luteolin and ethanol. J Mol Model, 2017, 23: 245.（通讯作者）
29. Yan-Zhen Zheng, Geng Deng, Qin Liang, Da-Fu Chen, et al. Antioxidant Activity of Quercetin and Its Glucosides from Propolis: A Theoretical Study. Scientific RePORTS, 2017, 7: 7543. （通讯作者）
30. Yan-Zhen Zheng, Yu Zhou, Qin Liang, Da-Fu Chen, et al. Solvent effects on the intramolecular hydrogen-bond and anti-oxidative properties of apigenin: A DFT approach. Dyes and Pigments, 2017,141: 179-187. （通讯作者）