一、基本情况
姓 名：史培颖
性 别：女
政治面貌：中共党员
职 称：副教授
研究方向：中药药效物质与作用机制；蜂产品功能开发
电子邮箱：peiyshi@126.com
二、受教育经历
2005.09-2010.06，浙江大学，药学院，硕博连读
2001.09-2005.06，华中科技大学同济医学院，药学院，本科
三、研究工作经历
2024.01至今，福建农林大学，蜂学与生物医药学院，副教授
2019.09-2023.12，福建农林大学，动物科学学院（蜂学学院），副教授
2016.09-2019.08，福建农林大学，蜂学学院，副教授
2010.08-2016.08，福建农林大学，蜂学学院，讲师
四、科研项目
(1) 福建省自然科学基金面上项目，荷花蜂花粉提取物抗异丙肾上腺素致小鼠心肌肥大的作用及机制研究，2023-2026，10万元，主持
(2) 国家自然科学基金面上项目，基于“分而治之”融合“效应加权”策略的冠心丹参方多成分整合药代动力学新方法研究，2020-2023，55万元，参与
(3) 福建省自然科学基金面上项目，五味子蜂花粉抗心肌缺血药效物质及作用机制研究，2018-2021，10万元，主持
(4) 福建省高校“新世纪优秀人才支持计划”，丹参、灯盏细辛注射液多成分药效作用权重表征及整合药代动力学新方法研究，2018-2021，6万元，入选者
(5) 福建省高校杰出青年科研人才培育计划，基于化学发光传感技术的苦碟子注射液整合药代动力学研究，2017-2020，8万元，入选者
(6) 国家自然科学基金青年项目，基于电化学传感技术的丹参注射液多成分整合药代动力学研究，2014-2016，23万元，主持
(7) 福建省自然科学基金青年项目，用于乳腺癌早期诊断及预后预测的血清代谢组学方法研究，2012-2014，4万元，主持
五、承担课程
本科生课程：药理学（双语课）（省级一流课程负责人）、蜂产品与保健、中药药理学、中药药理学实验、药代动力学、常用药物药理学
研究生课程：体内药物分析、蜂学高水平论文写作、蜜蜂研究进展
六、代表性论文
(1) Chenhui Zhong#, Liyuan Ke#, Fen Hu#, Zuan Lin, Shuming Ye, Ziyao Zheng, Shengnan Han, Zan Lin, Yuying Zhan, Yan Hu, Peiying Shi*, Lei Wen*, Hong Yao*. Ginsenoside Rb1 inhibits cardiomyocyte apoptosis and rescues ischemic myocardium by targeting Caspase-3, Journal of Pharmaceutical Analysis, 2025, 15: 101142.
(2) Rongfang Xie#, Chenlu Li#, Chenhui Zhong, Zuan Lin, Shaoguang Li, Bing Chen, Youjia Wu, Fen Hu, Peiying Shi*, Hong Yao*. Integration of virtual screening and proteomics reveals potential targets and pathways for ginsenoside Rg1 against myocardial ischemia, Journal of Ginseng Research, 2024, 48: 395-404.
(3) Zuan Lin, Rongfang Xie, Chenhui Zhong, Jianyong Huang, Peiying Shi*, Hong Yao*. Recent progress (2015-2020) in the investigation of the pharmacological effects and mechanisms of ginsenoside Rb1, a main active ingredient in Panax ginseng Meyer. Journal of Ginseng Research, 2022, 46: 39-53.
(4) Peiying Shi#, Rongfang Xie#, Panpan Wang, Yun Lei, Bing Chen, Shaoguang Li, Youjia Wu, Xinhua Lin, Hong Yao*. Non-covalent modification of glassy carbon electrode with isoorientin and application to alpha-fetoprotein detection by fabricating an immunosensor. Sensors and Actuators B: Chemical, 2020, 305: 127494.
(5) Peiying Shi, Xinhua Lin, Hong Yao*. A comprehensive review of recent studies on pharmacokinetics of traditional Chinese medicines (2014-2017) and perspectives. Drug Metabolism Reviews, 2018, 50 (2): 161-192.
(6) Zhiliang Li#, Jiali Yang#, Yang Sun, Shuo Han, Jietao Gong, Yi Zhang, Zhiyuan Feng, Hong Yao*, Peiying Shi*. Schisandra chinensis bee pollen extract inhibits proliferation and migration of hepatocellular carcinoma HepG2 cells via ferroptosis-, Wnt-, and focal adhesion-signaling pathways. Drug Design, Development and Therapy, 2024, 18: 2745-2760.
(7) Shihui Xie#, Shuo Han#, Jietao Gong, Zhiyuan Feng, Yang Sun, Hong Yao*, Peiying Shi*. Bee venom prompts the inhibition of gefitinib on proliferation, migration, and invasion of non-small cell lung cancer cells via EGFR-mediated autophagy. Toxicon, 2024, 251: 108149.
(8) Peiying Shi#,*, Tianyu Du#, Fei Meng#, Shihui Xie, Shuo Han, Jiali Yang, Yi Zhang, Yang Sun, Jietao Gong, Hong Yao*. Ethanol extract of propolis alleviates diabetic cardiomyopathy via JAK2/STAT3 signaling pathway. Journal of Functional Foods, 2023, 107: 105688.
(9) Peiying Shi#,*, Shihui Xie#, Jiali Yang, Yi Zhang, Shuo Han, Songkun Su, Hong Yao*. Pharmacological effects and mechanisms of bee venom and its main components: Recent progress and perspective. Frontiers in Pharmacology, 2022, 13: 1001553.
(10) Peiying Shi#, Qianqian Geng#, Lifu Chen, Tianyu Du, Yan Lin, Rongcai Lai, Fei Meng, Zhenhong Wu, Xiaoqing Miao, Hong Yao*. Schisandra chinensis bee pollen's chemical profiles and protective effect against H2O2-induced apoptosis in H9c2 cardiomyocytes. BMC Complementary Medicine and Therapies, 2020, 20: 274