一、基本情况
姓 名：杨玮娟
职 称：副教授, 硕士生导师
研究方向：核酸适配体筛选，小分子药物、兽残、农残快速分析方法构建。
电子邮箱：ywjbiochem@fafu.edu.cn或ywjbiochem@163.com
二、受教育经历
2017/2-2018/8，美国佛罗里达国际大学，博士后，（合作导师Yi Xiao教授）
2010/9 - 2015/7，福州大学化学学院，分析化学，博士，（导师付凤富教授）
2006/9 - 2010/7，福建农林大学生命科学学院，生物科学（基地班），学士
三、研究工作经历
2024/1-至今，福建农林大学蜂学与生物医药学院，生物制药系
2015/8 – 2023/12，福建农林大学植物保护学院，农药学与制药工程系
四、科研项目
1.国家自然科学青年基金项目21804020，2019.01.-2021.12. 主持
2.福建省科技厅引导性项目，2017Y0007, 2017.04-2020.03. (合作项目)
3.福建农林大学科技创新专项基金项目，KFB23025, 2023.10-2026.9. 主持
4.福建农林大学科技创新专项基金项目，CXZX2020018A, 2021.1-2022.12. 主持
五、承担课程
主讲本科生课程《制药过程安全与环保》《农药残留分析》，研究生课程《农业面源污染与生态治理》
六、近年代表论文：
1. Weijuan Yang*, Dongdong Luo, Siyu Zheng, Yiru Zhang, Zongwen Wang, Fengfu Fu*. Screening of cross-reactive aptamers for the detection of 24 quinolones by using a Liebig’s Law-guided parallel-series strategy. Analytical Chemistry, 2024, 96 (21), 8576-8585. (IF 6.7, 一区TOP)
2. Zemiao Wang, Feng Zhang, Ling Fang, Fengping Chen, Weijuan Yang*, Zongwen Wang*. Development of folding-based and signal-amplified fluorescence aptasensors using G-quadruplex quinclorac aptamer variants engineered via exonuclease digestion and circular dichroism spectroscopy, Sensors and Actuators B: Chemical, 2024,415,135996. (IF 8.0, 一区TOP)
3. Lin Zhang, Siqi Wu, Junfeng Liu, Meiling Ping*, Weijuan Yang*, FengFu Fu*,Isolation of aptamers with excellent cross-reactivity and specificity to sulfonamides towards a ratiometric fluorescent aptasensor for the detection of nine sulfonamides in seafood, Talanta, 2024,277,126380. (IF5.6,一区TOP)
4. Weijuan Yang*, Dongdong Luo, Yufan Xiao, Siyu Zheng, Zongwen Wang, Fengfu Fu,* Isolation and characterization of the quinclorac-specific aptamer toward a colorimetric sensor for the visual detection of quinclorac in water and soil. Sensors & Actuators: B. Chemical. 2023, 393, 134185. (IF 8.4，一区TOP)
5. Ruyi Xu, Chen Yang, Lin Huang, Wenchao Lv, Weijuan Yang*, Yongning Wu, FengFu Fu*, Broad-specificity aptamer of sulfonamides: isolation and its application in simultaneous detection of multiple sulfonamides in fish sample. Journal of Agricultural and Food Chemistry, 2022, 70, 37, 11804–11812. (IF 6.1，一区TOP)
6. Obtin Alkhamis#, Weijuan Yang#(共一), Rifat Farhana, Haixiang Yu, Yi Xiao*, Label-free profiling of DNA aptamer-small molecule binding using T5 exonuclease, Nucleic Acids Research, 2020, 48(20), e120. (IF 16.971，一区TOP)
7. Weijuan Yang#, Haixiang Yu#, Obtin Alkhamis, Yingzhu Liu, Juan Canoura, Fengfu Fu, Yi Xiao*. In vitro isolation of class-specific oligonucleotide-based small-molecule receptors. Nucleic Acids Research, 2019,47(12), e71. (IF 11.502，一区TOP)
8. Haixiang Yu, Weijuan Yang, Obtin Alkhamis, Juan Canoura, Kyung-Ae Yang, Yi Xiao*, In vitro isolation of small-molecule-binding aptamers with intrinsic dye-displacement functionality, Nucleic Acids Research, 2018, 46(8), e43. (IF 11.561，一区TOP)
9. Zhiqiang Chen, Xusheng Wang, Xian Cheng, Weijuan Yang*, Yongning Wu, FengFu Fu*. Specifically and Visually Detect Methyl-Mercury and Ethyl-Mercury in Fish Sample Based on DNA-Templated Alloy Ag–Au Nanoparticles. Analytical chemistry, 2018, 90(8): 5489-5495. (IF 6.350，一区TOP)
10. Zhiqiang Chen, Peipei Li, Xian Cheng, Weijuan Yang,* Yongning Wu, Qingai Chen, FengFu Fu*.Multicolor aptasensor based on DNA-induced Au−Ag nanorods for simultaneous and visual detection of inorganic and organic mercury. ACS Omega, 2019, 4, 15112−15119. (IF 2.584)
七、其他成果：
已授权专利：
1. 杨玮娟;罗冬冬;肖于凡;王宗文, 一种特异识别二氯喹啉酸的核酸适配体及其应用, ZL 2021 1 0478099.6
2. 杨玮娟，陈清爱，雷丽琴，傅依灵；一种基于DNA调控金-汞合金生长的甲基汞可视化检测方法，ZL.201911150449.5
参编教材：
1. 杨桂娣主编，现代仪器分析，ISBN：978-7-04-053528-0，高等教育出版社。
2. 杨桂娣主编，现代仪器分析实验数字课程，ISBN：978-7-89510-873-8，高等教育出版社。